Most Alphas get augmentation therapy once a week.
Like this:
A nurse inserts a needle into one of the Alpha's veins. Then the nurse attaches IV tubing to the needle and lets Alpha-1 Antitrypsin solution flow down from a hanging IV bag till it's empty.
Nurses often botch this job. Skill levels vary from superb to amateurish. Superb is rare, unacceptably poor is common.
The Infusion Nurses Society Standards of Practice say a nurse who fails twice to get an IV needle inserted should call a backup nurse or supervisor. This standard is routinely ignored all over the country.
Nurses often don't get adequate training, supervision or support for doing an IV procedure. They take two, three or more sticks for a single IV. They add unnecessary pain, fear and stress to the lives of their patients, and surely to their own.
It's a national disgrace.
PS: I'm grateful for the skilled IV nurses. One of them infused me for years, then taught me to do it for myself.